Lorne Monoclonal Fy^a blood grouping reagent contains human monoclonal antibodies diluted in a phosphate buffer containing sodium chloride and bovine albumin. The Lorne Human Anti-Fy^b blood grouping reagent is prepared from human serum diluted in a sodium chloride solution containing macromolecular potentiators and bovine albumin. Each reagent is supplied at optimal dilution for use with the indirect Coombs tube test and gel card techniques.